Physiologica1 materials relea-sed by B. megaterium as they change from vegetative to gemma during the fermentation are necessary for G. oxydans to grow and produce 2-KLG normaly.

• 发酵体系中巨大芽孢杆菌的存在是氧化葡萄糖酸杆菌的生长繁殖和合成2-KLG所必需的，发酵过程中巨大芽孢杆菌裂解所释放的活性物质可能是刺激氧化葡萄糖酸杆菌合成2-KLG的主要原因。