Peroxisome proliferator-activated receptors (PPARs), a family of transcription factors, play a crucial role in regulating glycemia,insulin sensitivity and the storage and catabolism of dietary fats.

• 近年来突破传统治疗药物的基本结构,研制开发以PPAR为靶点的新型抗糖尿病药物已成为药物研究的一大热点。