Permeability of BBB was determined by extravasation of the protein-bound Evans blue dye to cerebral cortex and further evaluated by immunohistochemical or electronmicroscopic method.

• BBB的通透性以结合有伊文氏蓝染料的血浆蛋白外渗进入脑组织的量以及免疫组化和电镜方法进行了测定。