PAF receptor antagonist BN52021 could inhibit the expression of ICAM-1mRNA and ELAM-1mRNA in cervical cord vascular endothelial cells, which significantly decreased Even content and water content in cervical cord tissues after trauma.

• PAF可使伤后血管内皮细胞ICAM－1mRNA、ELAM－1mRNA表达、伊文思蓝含量、水含量增加更为显著，PAF受体拮抗剂可抑制ICAM－1mRNA、ELAM－1mRNA表达，降低颈髓组织伊文思蓝含量及水含量。