Of the BCP double mutations, 5 patients (25%) in the mild hepatitis group, 4 patients (20%) in the moderate hepatitis group and 11 patents (55%) in the severe hepatitis group occurred the T1762/A1764 mutants.

• 42例不同病变程度的慢性乙型肝炎中，T1762/A1764双突变在轻度慢性肝炎中发生变异5例(25%25)，中度慢性肝炎发生变异4例(20%25)，重度慢性肝炎发生变异11例(55%25)。