ObjectiveBlood-brain barrier ( BBB) is composed of capillary endothelial cells, intercellular tight junction, base membrane, astroglial processes.

• 血脑屏障(blood brain barrier，BBB)由脑毛细血管内皮细胞及细胞间紧密连接、基膜、周细胞、星形胶质细胞脚板和极狭小的细胞外隙构成。