Objective:To investigate the effect of synthetic oligodeoxynucleotide containing CpG motifs (CpG ODN) on antibody production to recombinant hepatitis B surface antigen (rHBsAg) or hepatitis B vaccine respectively.

• 目的 :探讨合成含CpG基序的寡核苷酸 (CpGODN)对重组乙型肝炎表面抗原 (rHBsAg)及乙型肝炎疫苗增强小鼠特异性抗体产生的效应。