Objective: To study the effects of PolyI:C (Polyinosinic polycytidylic acid) on the incidence of diabetes and insulitis in the NOD (non-obese diabetic) mice, and change of Fas/ FasL protein and mRNA expression in pancreatic cells.

• 目的：观察免疫调节剂聚肌苷酸胞嘧啶核苷酸(PolyI：C，Polyinosinic polycytidylic)对自然发病的非肥胖性糖尿病(Non-obese diabetic，NOD)小鼠糖尿病发生和胰岛炎程度的影响以及干预后胰腺细胞Fas和Fas配体(FasL)的表达变化情况。