Objective: To prepare the insulin solid lipid nanoparticles(SLNs), insulin SLNs modified by wheat germ agglutinin(WGA), and to investigate the enhancing effect on insulin absorption through GI tract.

• 目的:制备胰岛素固体脂质纳米粒(SLNs)、麦胚凝集素(WGA)修饰固体脂质纳米粒(WGA-SLNs),研究其对口服吸收胰岛素的促进作用。