Objective: To explore the effect of suppressing PCGF4/Bmi-1 overexpression in CML cells line K562, on the proliferative rate of K562 cells .

• 目的:利用RNAi方法针对PCGF4/Bmi-1基因,抑制其在慢性髓性白血病K562细胞中的过表达,观察K562细胞的增殖性改变。