Objective: Diabetic nephropathy (DN) encompasses a complex of structure alterations, including the hypertrophy of glomerulus and renal tubule in early stage, and glomerulosclerosis, tubulointerstitial fibrosis (TIF) in late stage.

• 目的：糖尿病肾病(diabetic nephropathy, DN)的病理变化复杂，早期主要表现为肾小球和肾小管的肥大，晚期则表现为肾小球硬化及肾小管间质纤维化。