Objective To obtain the antigenic epitopes which can affinitive bind to theHCV(hepatitis c virus) polyclonal antibodies by using a phage 12-mer peptide libraryand to test the efficiency of converse biopannning by using negative serum.

• 目的筛选噬菌体展示随机12 肽库中可以与HCV 抗体阳性的血清特异性结合的序列,在HCV 表达的蛋白分子上找到这个抗原表位, 分析其序列、结构特点与功能的关系。 同时检验用阴性血清逆向筛选是否能提高筛选效率。