Objective To investigate pharmacokinetic parameters of panipenem in patients with respiatory disease, an HPLC method was proposed for assaying panipenem concentration in human plasma and in ureine .

• 目的建立高效液相色谱法测定人血浆样品及尿样品中帕尼培南浓度的定量分析方法,探讨帕尼培南在人体内药物动力学过程。