Objective To explore the effect of oral nursing care under the guidance of holistic viewpoint on prevention of stomatitis induced by chemotherapy with fluorouracil.

• 目的观察用整体护理观指导预防氟脲嘧啶类为主抗癌药物化疗所致口腔黏膜炎的效果。方法将448例恶性肿瘤病人随机分为实验组和对照组。