Objective In order to observe the growth and metastasis of the tumor directly,a new orthotopic retinoblastoma model was established with human RB cells expressing green fluorescent protein (GFP).

• 目的应用绿色荧光蛋白(GFP)基因标记人类视网膜母细胞瘤(RB)细胞,建立新型裸鼠原位移植瘤模型,探讨RB的生长和转移特征。