Object: The resistance and cross resistance of HSV 1 to antiviral antibiotic 17997 were studied in vitro and in vivo .

• 目的 体外训练单纯疱疹病毒 1型 (HSV- 1)对抗生素 17997的耐药突变及体内、外研究抗生素17997与阿昔洛韦 (ACV)的交叉耐药。