No matter of using which method, it all takes much time or costs much money.Unless researchers have enough funds, few are willing to use SMM or CVM to evaluate the health benefit.

• 尽管有上述方法可参考使用，但经常矌日费时、经费庞大，因此过去除非研究资源足够，否则很少有研究机构愿意从事此种耗费成本又矌日耗时的工作；