Moreover,CME significantly inhibited the histamine-induced cutaneous capillary permeability,the paw edema caused by 5-HT and licking response induced by 4-aminopyridine in mice.

• 对二甲苯所致小鼠耳肿胀、5-羟色胺所致小鼠足肿胀、组胺所致小鼠皮肤血管通透性增高具有显著对抗效果,延长4-氨基吡啶所致小鼠舔体潜伏期、减少舔体次数。