More than 3 000 vitamin D3 analogues have been synthesized in order to reduce the calcium side effects while maintaining the transactivation potency of these ligands.

• 为了减少钙血症等不良反应，并使活性维生素几的各种生理学作用相分离，到目前为止已经合成出3000余个活性维生素几衍生物。