Mice were respectively immunized by the conjugates, unconjugated ACPS, BOMPC and simple mixture of ACPS and BOMPC in the same procedure, then the immunogenicity of the conjugates was determined by ELISA, bactericidal test and Western blotting.

• 偶联物、未偶联的荚膜多糖、B群外膜蛋白复合物及A群荚膜多糖和B群外膜蛋白复合物简单混合物按相同程序免疫小鼠获得抗体 ,经ELISA、杀菌力试验和Westernblotting测定了偶联物的免疫原性。