Mice and rats were divided randomly in several groups: DES groups, U+DES groups, AAF groups, U+AAF groups, Urethane group, control group and solvent group.

• 小鼠和大鼠均设DES单独作用组、U+DES联合作用组、AAF组、U+AAF组、U对照组、正常对照组、溶剂对照组。