Methoxymethyl chloride was used as a facile protecting group for free hydroxyls in the preparation of polyhydroxy derivatives of chalkones, flavones and isoflavones.

• 通过氯甲基甲醚保护相应醛、酮的酚羟基先合成查尔酮,进而方便地制备多羟基黄酮或异黄酮化合物。