Methods: The rats model depending on diamorphine was established.The pathological changes of glomerules and renal tubules were observed by light microscopy after HE,PAS,PASM coloration.

• 方法:建立海洛因依赖大鼠模型,对肾组织分别行HE、PAS、PASM染色后光镜观察肾小球、肾小管病变情况。