Methods: Exposed ECs co-cultured with VSMCs to physiological laminar shear stress and PGI2 was measured by Radioimmunoassay.

• 方法：应用流动腔系统，对与平滑肌细胞联合培养的内皮细胞施加生理大小的切应力，以放免分析法检测内皮细胞分泌PGI2的变化。