Methods: 220 C57BL/6 mice, 6-8 weeks old, 20-25 gram, were randomly divided into normal control, 3 hour, 12-48 hour, 5-7 day, 10-12 day post trauma.

• 方法：选取雄性C57BL/6小鼠220只，6-8周，体重20-25克，分为正常对照组和实验组。