Methods The rabbits were cannulated with a silicone tube in the common bile duct and the blank bile was collected.The rabbits were then administered intravenously with meropenem.

• 方法 家兔行胆总管造瘘术，先留取空白胆汁，静脉注射美罗培南后分别于不同时间点采集胆汁标本。