Methods Sixty-four patients with first episode depression were evaluated by HAMD 17 and P300 and MMN tests were performed at the baseline and week 12.

• 方法对64例抑郁症首次发病患者于治疗基线和治疗12周采用汉密顿抑郁量表(HAMD)17项评定症状严重程度，采用脑诱发电位仪进行事件相关电位P300和MMN检测，并与36例健康人进行P300和MMN指标对照研究。