Methods Immunohistochemical method was used to detect the P16,cyclin D 1 , P53 and mdm2 protein expression in 21 cases of exfoliated urothelial cells of the TCC of urinary bladder.

• 方法 :用免疫组织化学S -P法检测 2 1例膀胱TCC尿脱落细胞及组织中P16、cyclinD1、P5 3、mdm2蛋白的表达。