Methods Gated by CD3 and SSC, the changes of CTLA-4, PD-1, and CD25 on CD3+CD4+ cells were evaluated in 38 new diagnosed cases with MDS(RA 17, RAS 1, RAEB 14. RAEB-t 6) and 11 normal controls respectively by directive immune labels.

• 方法以CD3和侧向角设门,采用直接免疫三标法以流式细胞术检测38例初治MDS患者(RA 17例、RAS 1例、RAEB 14例、RAEB-t 6例)及11例正常对照组外周血CD3+ CD4+细胞上CTLA-4、PD-1、CD25数量和比例变化,并探讨与疾病进展的关系。