Methods Bilateral radius bone defect models (10 mm in length) were made in 54 rabbits with 6 different methods,group A:rhIGF-I/CHA/ARBM,group B:CHA/ARB M,group C:rhIGF-I/CHA,group D:CHA,group E:autograft and group F:no implant was used as control group.

• 方法54只家兔制双侧桡骨干11mm全层缺损模型,分六组移植相应材料:A组(rhIGF-I/CHA/ARBM),B组(CHA/ARBM),C组(rhIGF-I/CHA),D组(CHA),对照组为E组(自体骨)和F组(缺损旷置),每组9只各18侧。