Methods After the establishment of full-thickness dermal wounds with the diameter of 4 cm on the back of 6 minitype pigs,the specimens were collected from wound edge and wound center immediately,and on the day 3,6,9,12,15,20,25 and 40 after injury.

• 方法在6头小型猪的背部各造成8个直径为4cm的圆形全层皮肤缺损创面。 在创面形成后当日及3、6、9、12、15、20、25和40d,取创面中心及创面边缘的组织,采用免疫组织化学染色和原位杂交检测bax和baxmRNA的表达。