Methods 60 New Zealand white rabbits were studied as object in our experiment. The knee joint was fixed in plaster cast in extention posture to establish animal model. All rabbit were distributed random to A group(fixed for 4 weeks)and B group(8weeks).

• 方法以新西兰白兔 60只为研究对象，管型石膏固定的方法建立 OA动物模型，随机分为制动 4周组（ A组），制动 8周组（ B组）。