Method:Discus s the relations between the rational use of antimicrobial agents and the post ef fect, time dependence, concentration dependence, resistent of antimicrobial agen ts.

• 方法：讨论抗菌药物后效应、时间依赖性和浓度依赖性抗菌药物以及细菌耐药问题与合理使用抗菌药物的关系。