Method: The berberine in Rhizoma coptidis and zuojing pill were pre-separated with macroporous ad.sorptive resin D101 , and the contents of berberine were determined by RP-HPLC.

• 方法:对黄连及左金丸中化学成分用大孔吸附树脂D101进行预分离,反相高效液相色谱法测定其小檗碱的含量。