Method: Rats of dependence on morphine was treated with Bup; the scores of withdrawal symptoms and time spent in morphine-paired box was measured at the 24 hour, 72 hour and on the 8th day in test rates .

• 方法··:以生理盐水为对照组 ,应用丁丙诺啡对吗啡依赖大鼠进行脱毒治疗 ,分别于停用吗啡24h,72h,8d观察其对湿狗样抖动、齿颤等戒断症状的影响及位置偏爱实验吗啡侧停留时间。