Methamphetamine is a potent neurotoxin, shown to cause dopaminergic degeneration.[11][12] High doses of methamphetamine produce losses in several markers of brain dopamine and serotonin neurons.

• 甲基苯丙胺是种很强的神经毒素，会造成多巴胺能退化。大剂量的甲基苯丙胺造成大量脑多巴胺，复合胺神经细胞死亡。