Medthod:Urine pyridinoline and deoxypyridinline were measured by ELISA assay in 26 patients with local cancer and 69 advanced cancer patients with or without bone metastases.

• 方法：采用ELISA方法检测了26例限局性恶性肿瘤、35例进展期肿瘤骨转移阴性和34例骨转移阳性的尿吡啶酚和脱氧吡啶酚水平。