MSP analysis showed CpG islands of PRA & PRB promoters were hypermethylated without unmethylation bands and PRAB & PRB mRNA expressions were inactivated in the three leukemia lines HL-60, K562, Jurkat.

• MSP检测白血病细胞株L-60、K562、Jurkat PR启动子甲基化显示：在三株白血病细胞，PRA、PRB启动子CpG岛处于高甲基化状态，而且PRAB、PRB mRNA表达失活。