METHODS The toxicity, pyrogen, hemolytic activities and immunogen were detected by means of animal test, cell culture, hemolysis test and histochemical technique.

• 方法制备CPC/BMP及CPC骨块,通过体外实验、细胞培养、动物实验等方法观察其毒性、免疫原性、对血液系统的影响等生物相容性指标。