KLF6 gene suppresses hepatocellular carcinoma cell proliferation,which may be partially associated with the upregulation of p21(WAF1) expression.

• KLF6基因表达水平的下降可能在原发性肝癌发病机制中起到一定作用。 上调p21WAF1表达是KLF6基因抑制肝癌细胞增殖的重要途径.