KEY WORDS: In situ formed orifice technology; two sides drilling technology; differentially release technology; propranolol hydrochloride; gliclazide; osmotic pump controlled release dosage form

• 关键词：原位致孔技术，双面打孔技术，异步释放技术，盐酸普萘洛尔，格列齐特，渗透泵控释制剂