It was indicated by the immunogenic experiments that the prepared OMPA possessed good immunogenicity and had a broadly cross reactivity with the other serotypes.

• 免疫原性实验表明:所制备的外膜蛋白A具有优良的免疫原性,对5种血清型肺炎球菌均有较广泛的交叉免疫效果,可作为新一代的肺炎球菌疫苗成分。