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It was concluded that the expression of FasL on IL 2AK and IL 12AK and the Fas on tumor cells had positive correlation with the apoptosis of tumor cells; and Fas and FasL was one of pathways that IL 2AK and IL 12AK killed tumor targets.
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由此推论,Fas-FasL途径是IL-2与IL-12诱导活化的LAK细胞杀伤肿瘤的途径之一,淋巴细胞致肿瘤凋亡分别与淋巴细胞FasL表达和肿瘤细胞Fas表达一致。
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