It suggests that rhG CSF may enhance the sensitivity of drug resitant AML cells to Ara C in vitro by recruiting blasts into the cell cycle. There for , its use in treating AML Patients of drug resistance with rhG CSF and Ara C was recommended.

• rhG－CSF可能通过促进耐药AML细胞进入增殖周期，而增强Ara－C对耐药AML细胞的毒性，从而具有耐药的逆转效应，预示着rhG－CSF与Ara－C联合运用治疗耐药AML的潜在价值