It is concluded that the region of loss at 13q14 locates between D13S319 and D13S25 in CLL, and the I-FISH is a rapid and sensitive technique for analysis of del(13q14) in CLL.

• 结论:CLL患者13q14缺失区域可能位于D13S319和D13S25之间,FISH是一种检测del(13q14)异常快速而准确的方法。