In rat CPP model, agmatine (0.75-20 mg/kg, sc) co-administered with morphine inhibited the development, expression and the priming of CPP induced by morphine.

• 在条件性位置偏爱(CPP)模型上；吗啡处理大鼠9d可形成明显CPP。 胍丁胺(0.；75-20mg/kg；sc)伴随吗啡给药抑制CPP的形成、表达和小剂量吗啡诱导的复发。