In order to raise vigilance and reduce the incidence of daunomycin-related cardiotoxicity,the clinical patterns of such toxicity and the safety threshold of the daunomycin dosage were presented.

• 结果发现,102例接受柔红霉素治疗患儿中有13例发生心脏毒性,表现为充血性心力衰竭、扩张性心肌病和各种心律失常。