In many protein aggregation diseases, incorrectly folded proteins self-associate, forming fiber-like aggregates that cause brain cell death and dementia.

• 在很多蛋白质凝聚的疾病中，错误折叠的蛋白自我结合，形成纤维样的凝集体，从而导致脑细胞死亡和老年痴呆。