In PTX rats, the cAMP and CaM in renal cortics and the CaM in the brain was decreased,but the 45Ca uptake in brain synaptosomes was increased significantly.

• PTX鼠肾脏皮质cAMP和钙调素(CaM)含量明显减少,大脑皮层和纹状体CaM也明显降低,而脑突触体~(45)Ca摄取量显著增高。