Histamine receptor antagonist can prevent and ameliorate airway remodeling and acid-base imbalance in asthma of guinea pig.

• 结论:组胺在哮喘气道重塑中起介导作用,组胺受体拮抗剂对防治哮喘气道重塑及酸碱平衡紊乱有一定作用。